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100 Summer Street is a high-rise building located in downtown Boston, Massachusetts. The building stands at 450 feet (137 meters) with 32 floors, over 1 million square feet (over 92,00m^2) of office space, and was completed in 1974. It is currently the 23rd-tallest building in Boston. The architectural firm who designed the building was Welton Becket and Associates. 100 Summer Street is notable for the distinctive bronze tint of its windows.

1000 Second Avenue is a 493 ft (150 m) tall skyscraper in Seattle, Washington. It was completed in 1987 and has 43 floors. Originally known as the Key Tower, it is the 14th tallest building in Seattle.

1001 Woodward, also known as the First Federal Building (for its original lead tenant, First Federal Savings and Loan of Detroit), is a mixed-use skyscraper in downtown Detroit, Michigan. The building is located just south of the neighboring David Stott Building, and can be found at the corner of Woodward Avenue and Michigan Avenue overlooking Campus Martius Park. Constructed from 1963 to 1965, the 25 story building employs the International style of architecture.

101 California Street is a 48-storey office building completed in 1982 in the Financial District of San Francisco, California. The 183 m (600 ft) tower providing 1,200,000 sq ft (111,000 m) of office space is bounded by California-, Davis-, Front-, and Pine Streets near Market Street. The faceted cylindrical tower features a seven story, glass enclosed lobby and a granite plaza with flower beds and a fountain.

101 Clarendon Street, also known as Columbus Center, is a proposed skyscraper planned for Boston, Massachusetts. If completed, it would stand as the 25th-tallest building in Boston. Continuing on the trend established by the Prudential Tower in 1964, the completed building will conceal more of the Massachusetts Turnpike by utilizing air rights above it.

101 Federal Street is a skyscraper on Federal Street in the Financial District neighborhood of Boston, Massachusetts. Completed in 1988, the 116 meter (381 ft) building was designed by Kohn Pedersen Fox Associates PC. The building is also known as 75 - 101 Federal Street These buildings contain 800,000 sq ft (74,000 m) of office space. The State Street Trust Building is the 75 Federal Street portion of the building. The Art Deco building was designed by Thomas M. James in 1929..

101 Montgomery is a skyscraper in San Francisco, California. The building rises 404 feet (123 meters) in the northern region of San Francisco’s Financial District. It contains 28 floors, and was completed in 1984. 101 Montgomery is currently tied with Embarcadero West as the 39th-tallest building in the city. The building's developer was Cahill Contractors. The building has earlier served as the headquarters of Charles Schwab & Company.

101 Park Avenue is a 629-foot (192 m) tall skyscraper in New York City, New York. It was completed in 1979 to 1982 and has 49 floors. Eli Attia Architects designed the building, which is the 64th tallest in New York. It was used as the facade of the fictional "Pemrose building" in the 1987 film The Secret of My Success, as well as the fictional "Clamp Tower" in the 1990 film Gremlins 2.

101 Second Street is an office tower located in the South of Market district in San Francisco, California on Mission Street. The 108 m (354 ft) building was completed in 1999 and has 26 floors with 388,000 sq ft (36,000 m) for offices. This is one out of several new highrise projects completed or under construction on Mission Street since 2000.

101 West Ohio is a high rise in Indianapolis, Indiana. It was completed in 1987 and is currently the eighth-tallest building in the city. It is primarily used for office space.